Email: ebolea@unizar.es
Organization Type: University
Organization Name: Universidad de Zaragoza
Short Biography: Eduardo Bolea Fernández holds a Bachelor's and Master's in chemistry from the University of Zaragoza. He earned his Ph.D. at Ghent University in 2017. He was granted postdoctoral fellowships from the Research Council of Ghent University (2017) and the Research Foundation - Flanders (2019 and 2022). Eduardo was recognized with the IUPAC-Solvay International Award for Young Chemists in 2018 and the 2022 Young Scientist Winter Conference Award in Plasma Spectrochemistry. He is currently a Ramón y Cajal fellow at the University of Zaragoza. Eduardo's research focuses on the development of innovative analytical methods and their application in the context of metallomics and nanotechnology. Within his research group, he initiated, led, and consolidated the research line of single-event ICP-MS, enabling the characterization of nano/micro particles and individual cells. Very recently, he has been selected as the winner of the Emerging Leader in Atomic Spectroscopy Award. So far, Eduardo is (co)author of 44 publications in peer-reviewed international journals (43/44 Q1), that have gathered approx. 1800 citations (h-index of 23 and i10-index of 30) according to Google Scholar. He has presented his work in over 50 international conferences and workshops.?
Email: Heidi.Goenaga-Infante@lgcgroup.com
Organization Type: Non-academic institution
Organization Name: LGC Limited
Short Biography: Heidi obtained her PhD from Oviedo University, Spain. She joined LGC as senior researcher in speciation analysis in 2003. Currently, she is a Science Fellow of LGC and the Principal Scientist and Team Leader of the Inorganic Analysis team of fourteen PhDs and postgraduate scientists. She is the UK representative at the Inorganic Analysis Working Group of the CCQM, the international Consultative Committee for Metrology in Chemistry. She chairs the Editorial Board of the “Journal of Analytical Atomic Spectrometry” and is a member of the International Advisory Boards of “Analytical and Bioanalytical Chemistry” and “Metallomics”. She is the Government Chemist representative on the Nanomaterials Environment and Health Government Group chaired by DEFRA and the LGC representative at ISO TC 24 (Particle characterisation). She has acted as the coordinator of the EU EUROPEAN Metrology Research Proposal (EMRP) NanoChop “Chemical, Optical and Biological characterisation of nanomaterials in biological samples”. She is the leading author of over a 140 scientific research papers and 6 book chapters. Heidi was awarded the 2020 Lester W. Strock Award from SAS.
Added Value: Our group expertise currently lies in trace element speciation analysis, metallomics research, the characterisation of nanomaterials, high accuracy isotope ratio analysis, quantitative elemental bioimaging and the characterisation of “speciated” reference materials and standards. As part of the Inorganic Analysis team that I supervise at LGC, the predoctoral researcher will have access to training on metrological aspects of single particle and single cell analysis including improved calibration strategies and measurement uncertainty calculation. The researcher will also get familiar with market assessment for the distribution of reference materials as well as all the aspects involved in reference material production, increasing her/his employability in this sector, and networking with international partner institutions, working together in European/International projects.
Email: Frank.Vanhaecke@UGent.be
Organization Type: University
Organization Name: Ghent University
Short Biography: Prof. Dr. Frank Vanhaecke is senior full professor in analytical chemistry at Ghent University, where he leads the A&MS research unit. The research carried out in the A&MS-UGent unit has so far resulted in >400 papers in peer-reviewed international journals that, until now, have gathered ca. 22.000 citations according to Google Scholar, providing Frank with an h-index of 73 and an i10-index of 394. In addition, Frank has also been co-author of 17 book chapters and editor of one book. He has also presented the results of his group via >60 invited/plenary lectures on major international conferences and via ca. 30 invited lectures at universities & research institutions. In 2011, Frank received a ‘European Plasma Spectrochemistry Award’, in 2013, he was designated ‘Fellow of the Society for Applied Spectroscopy – SAS’ and in 2017, he received the ‘Lester Strock Award’ from SAS.
Added Value: The A&MS-UGent unit has a longstanding interest in addressing real-world issues in biomedical and clinical contexts. The unique array of instrumentation at A&MS complements that available at MARTE and LGC, encompassing advanced tools for single-particle/cell analysis and laser ablation ICP-MS. I also have an extensive history of collaboration with Dr. Eduardo Bolea Fernández, a distinguished former A&MS group member. Our collaboration continued closely over the years, even after he joined the MARTE research group at the University of Zaragoza. The collaboration between MARTE and A&MS has been longstanding, spanning over 25 years. Eduardo and I maintain a close working relationship, including the remote co-mentoring of two PhD students, facilitated by the available technical resources at our disposal.
Description: MARTE (Métodos de Análisis Rápido con Técnicas Espectroscópicas; https://marte.i3a.es) is a multidisciplinary official research group (E43_20R) composed of staff from the University of Zaragoza belonging to the Institute of Engineering of Aragon (I3A) (Dr. M. Resano, Dr. M.T. Aramendía Marzo, Dr. E. García-Ruiz, and Dr. E. Bolea Fernández), and staff from the University Hospital Miguel Servet (Dr. L. Rello, Dr. E. Martínez Morillo, E. García González, G. Hernández de Abajo) and from the Technological Institute of Aragón (Dr. E. Mozas García). Besides, postdoctoral researchers (Dr. A. Rua Ibarz and Dr. F. V. Nakadi) and predoctoral students (A. Marques de Souza, A. Bazo Sánchez, J. Rayos Hurtado, B. Moreira Freire, A. García García) need to be mentioned. MARTE research activity focuses on elemental and isotopic analysis at trace levels, with special attention to the development of biomedical applications. MARTE actively cooperates with universities and industrial partners, and five of them have been selected for this application due to their high added value in terms of predoctoral formation. They are all large institutions (hundreds of people), actively participating in international projects.
Description: Advancing ICP-mass spectrometry for nano/micro entity quantification Progress in atomic spectrometry plays a pivotal role in acquiring ever more information at the micro- and nano-scale, particularly when dealing with low volume (or mass-limited) samples and discrete entities, such as nanoparticles, micro/nano plastics and single cells. Inductively coupled plasma-mass spectrometry (ICP-MS) is a powerful technique for trace element and isotopic analysis, with substantial enhancements in instrument performance over the past four decades. Nevertheless, the conventional sample introduction system in ICP-MS has lagged in progress and still often relies on methods consuming up to 1 mL of sample per minute. This approach seems unreasonable considering the improved sensitivity of contemporary ICP-MS instrumentation, and contradicts the principles of green-chemistry, which aim for a more sustainable future. To overcome these constraints, this project aims to develop innovative methods for obtaining comprehensive information from increasingly smaller sample amounts. These proposed methods hold considerable potential for applications in health research and medical diagnosis, promising to elevate the capabilities of atomic spectrometry to unprecedented levels.
Description: The proposed project is in perfect alignment with the main goals of Horizon Europe, as it seeks to advance scientific and technological excellence. Moreover, the project directly addresses a policy priority in the area of Health, which is of utmost importance for society. The emphasis on international cooperation will foster collaboration and knowledge exchange between research groups, enhancing the project's impact and contributing to a global research network. In addition, the project's adherence to Open Science principles ensures transparency, accessibility, and reproducibility of research outcomes, promoting a culture of open collaboration and data sharing within the scientific community. Furthermore, the project's focus on Green Chemistry principles and the Circular Economy demonstrates a commitment towards sustainability and responsible research practices. The cross-fertilization approach proposed will strengthen collaborations with industry partners and other research institutions. By addressing real-world problems faced by collaborators and offering state-of-the-art analytical methodologies, the project will not only provide custom analytical solutions but will also inspire new research questions and targeted method development. On the social front, the project's focus on advancing ICP-MS for nano/micro entity quantification, focusing on nanoparticles and cells, will contribute to cutting-edge research in the field of bioanalysis. By enhancing our understanding of individual cells and nanoparticles behavior, the project can lead to groundbreaking discoveries with potential implications for human health, disease diagnosis, and environmental protection. Moreover, the project's collaboration with industry/policymaker partners (e.g., LGC, Perkin Elmer, VITO, etc) and the development of custom analytical methods will directly benefit various sectors, such as healthcare, biotechnology, and environmental monitoring. The effective transfer of knowledge for biomedical aspects is ensured through the participation of HUMS members.